239 research outputs found

    Geometrical phases and entanglement in real space for 1D SSH topological insulator: effects of first and second neighbor-hoppings interaction

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    The hybrid atoms-cell site entanglement in a one-dimensional Su-Schrieffer-Heeger (SSH) topological insulator with first and second neighbor hopping interaction in space representation of finite chains is analyzed. The geometric phase is calculated by the Resta electric polarization and the entanglement in the atomic basis by the Schmidt number. A relation between entanglement and the topological phase transitions (TPT) is given since the Schmidt number has critical points of maximal entangled (ME) states in the singularities of the geometrical phase. States with second-neighbors have higher entanglement than first-order hopping. The general conditions to produce ME hybrid Bell states and the localization-entanglement relation are given.Comment: 6 pages and 4 figure

    Carbon and oxygen in HII regions of the Magellanic Clouds: abundance discrepancy and chemical evolution

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    We present C and O abundances in the Magellanic Clouds derived from deep spectra of HII regions. The data have been taken with the Ultraviolet-Visual Echelle Spectrograph at the 8.2-m VLT. The sample comprises 5 HII regions in the Large Magellanic Cloud (LMC) and 4 in the Small Magellanic Cloud (SMC). We measure pure recombination lines (RLs) of CII and OII in all the objects, permitting to derive the abundance discrepancy factors (ADFs) for O^2+, as well as their O/H, C/H and C/O ratios. We compare the ADFs with those of other HII regions in different galaxies. The results suggest a possible metallicity dependence of the ADF for the low-metallicity objects, but more uncertain for high-metallicity objects. We compare nebular and B-type stellar abundances and we find that the stellar abundances agree better with the nebular ones derived from collisionally excited lines (CELs). Comparing these results with other galaxies we observe that stellar abundances seem to agree better with the nebular ones derived from CELs in low-metallicity environments and from RLs in high-metallicity environments. The C/H, O/H and C/O ratios show almost flat radial gradients, in contrast with the spiral galaxies where such gradients are negative. We explore the chemical evolution analysing C/O vs. O/H and comparing with the results of HII regions in other galaxies. The LMC seems to show a similar chemical evolution to the external zones of small spiral galaxies and the SMC behaves as a typical star-forming dwarf galaxy.Comment: Accepted for publication in MNRAS, 17 pages, 11 figures, 8 table

    The 8-Odorant Barcelona Olfactory Test (BOT-8): Validation of a New Test in the Spanish Population During the COVID-19 Pandemic

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    COVID-19; Pèrdua d'olfacte; Prova de l'olfacteCOVID-19; Loss of smell; Smell testCOVID-19; Pérdida de olfato; Prueba del olfatoBackground and objective: Most smell tests are difficult to implement in daily clinical practice owing to their long duration. The aim of the present study was to develop and validate a short, easy-to-perform, and reusable smell test to be implemented during the COVID-19 pandemic. Methods: The study population comprised 120 healthy adults and 195 patients with self-reported olfactory dysfunction (OD). The 8-Odorant Barcelona Olfactory Test (BOT-8) was used for detection, memory/recognition, and forced-choice identification. In addition, a rose threshold test was performed, and a visual analog scale was applied. The Smell Diskettes Olfaction Test (SDOT) was used for correlation in healthy volunteers, and the University of Pennsylvania Smell Identification Test (UPSIT) was used for patients with OD to establish cut-offs for anosmia and hyposmia. In order to take account of the COVID-19 pandemic, disposable cotton swabs with odorants were compared with the original test. Results: In healthy persons, the mean (SD) BOT-8 score was 100% for detection, 94.5% (1.07) for memory/recognition, and 89.6% (0.86) for identification. In patients with OD, the equivalent values were 86% (32.8), 73.2% (37.9), and 77.1% (34.2), respectively. BOT-8 demonstrated good test-retest reliability, with agreement of 96.7% and a quadratic k of 0.84 (P<.001). A strong correlation was observed between BOT-8 and SDOT (r=0.67, P<.001) and UPSIT (r=0.86, P<.001). Agreement was excellent for disposable cotton swabs, with a k of 0.79 compared with the original test. The cut-off point for anosmia was ≤3 (area under the curve, 0.83; sensitivity, 0.673; specificity, 0.993). Conclusion: BOT-8 offers an efficient and fast method for assessment of smell threshold, detection, memory, and identification in daily clinical practice. Disposable cotton swabs with odorants proved to be useful and safe during the COVID-19 pandemic

    Alcohol and early mortality (before 65 years) in the ‘seguimiento Universidad de Navarra’ (SUN) cohort: does any level reduce mortality?

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    The aim of this study was to assess the association between alcohol intake and premature mortality (younger than 65 years) and to explore the effect of potential alcohol underreporting by heavy drinkers. We followed-up 20 272 university graduates. Four categories of alcohol intake were considered (abstainer, light, moderate and heavy consumption). Repeated measurements of alcohol intake and updated information on confounders were used in time-dependent Cox models. Potential underreporting of alcohol intake by some heavy drinkers (likely misclassified as light or moderate drinkers) was explicitly addressed in an attempt to correct potential underreporting by using indirect information. During 12·3 years of median follow-up (interquartile range: 6·8–15·0), 226 participants died before their 65th birthday. A higher risk of early mortality was found for the highest category of alcohol intake (≥50 g/d) in comparison with abstention (multivariable-adjusted hazard ratio (HR) = 2·82, 95 % CI 1·38, 5·79). In analyses of alcohol as a continuous variable, the multivariable-adjusted HR was 1·17 (95 % CI 1·08, 1·26), for each 10 g/d of alcohol. This harmful linear association was present both in uncorrected models and in models corrected for potential underreporting. No significant inverse association between light or moderate alcohol intake and premature mortality was observed, even after correcting for potential misclassification. Alcohol intake exhibited a harmful linear dose–response association with premature mortality (<65 years) in this young and highly educated Mediterranean cohort. Our attempts to correct for potential misclassification did not substantially change these results

    Analgesia during Parturition in Domestic Animals: Perspectives and Controversies on Its Use

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    Published: 6 October 2022This article analyzes the physiological role of pain during parturition in domestic animals, discusses the controversies surrounding the use of opioids, non‐steroidal anti‐inflammatory drugs (NSAIDs), and local analgesics as treatments during labor, and presents the advantages and disadvantages for mother and offspring. Labor is a potentially stressful and painful event, due to the contractions that promote expulsion of the fetus. During labor, neurotransmitters such as the prostaglandins contribute to the sensitization of oxytocin receptors in the myometrium and the activation of nociceptive fibers, thus supporting the physiological role of pain. Endogenously, the body secretes opioid peptides that modulate harmful stimuli and, at the same time, can inhibit oxytocin’s action in the myometrium. Treating pain during the different stages of parturition is an option that can help prevent such consequences as tachycardia, changes in breathing patterns, and respiratory acidosis, all of which can harm the wellbeing of offspring. However, studies have found that some analgesics can promote myometrial contractility, increase expulsion time, affect fetal circulation, and alter mother–offspring recognition due to hypnotic effects. Other data, however, indicate that reducing the number of uterine contractions with analgesics increases their potency, thus improving maternal performance. Managing pain during labor requires understanding the tocolytic properties of analgesics and their advantages in preventing the consequences of pain.Daniel Mota-Rojas, Antonio Velarde, Míriam Marcet, Rius, Agustín Orihuela, Andrea Bragaglio, Ismael Hernández, Ávalos, Alejandro Casas, Alvarado, Adriana Domínguez, Oliva and Alexandra L. Whittake

    The neurobiology of pain and facial movements in rodents: clinical applications and current research

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    One of the most controversial aspects of the use of animals in science is the production of pain. Pain is a central ethical concern. The activation of neural pathways involved in the pain response has physiological, endocrine, and behavioral consequences, that can aect both the health and welfare of the animals, as well as the validity of research. The strategy to prevent these consequences requires understanding of the nociception process, pain itself, and how assessment can be performed using validated, non-invasive methods. The study of facial expressions related to pain has undergone considerable study with the finding that certain movements of the facial muscles (called facial action units) are associated with the presence and intensity of pain. This review, focused on rodents, discusses the neurobiology of facial expressions, clinical applications, and current research designed to better understand pain and the nociceptive pathway as a strategy for implementing refinement in biomedical research.Adriana Domínguez-Oliva, Daniel Mota-Rojas, Ismael Hernández-Avalos, Patricia Mora-Medina, Adriana Olmos-Hernández, Antonio Verduzco-Mendoza, Alejandro Casas-Alvarado, and Alexandra L. Whittake

    Dry matter distribution of banderita grass [Bouteloua curtipendula (Michx.) Torr.] at different plant strata

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    Objective: To evaluate the dry matter distribution of banderita grass [Bouteloua curtipendula (Michx.) Torr.] in different plant strata. Design/Methodology/Approach: A randomized block experimental design with five repetitions was used for the experiment. Each repetition consisted of three plants which were evaluated at different days after sowing (DAS), in three different plant strata: basal stratum (BS), middle stratum (MS), and upper or apical stratum (AS). The following variables were evaluated: dry matter yield (DMY), morphological composition (MC), leaf area (LA), plant height (PH), leaf:stem ratio (L:SR), and aerial part:root ratio (Ap:rR). An analysis of variance was performed, using the PROC GLM procedure of the SAS software; in addition, a comparison of means was carried out using Tukey’s test (α&lt;0.05). Results: SB made a greater contribution to DMY at 50 DAS, with a 16 g DMY plant-1 average, followed by MS, with 9 g DM plant-1, and AS with 3 g plant-1. The MC (g) in the BS registered that the stem made a greater contribution than the rest of the components (average: 12.3 g plant-1), while leaves from the MS and AS made the greatest contribution (2.6 g plant-1) up to 64 DAS. However, they were surpassed by the stem in the MS and by the inflorescence in the AS. In addition, BS registered the highest LA (173.4 cm2). The largest PH was recorded at 120 DAS (96 cm). The highest L:SR ratio reached 1.10 at 50 DAS, while Ap:rR recorded 3.82 at 92 DAS. Study Limitations/Implications: The experiment was carried out under greenhouse conditions. Therefore, any extrapolation or comparison with field conditions should be done with caution. Findings/Conclusions: The basal and middle part of a banderita grass (Bouteloua curtipendula) plant contains the highest forage accumulation (mainly in the leaves and the stem), while the highest biomass content in the apical part is produced by the inflorescence

    Assessment of Pain and Inflammation in Domestic Animals Using Infrared Thermography: A Narrative Review

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    Pain assessment in domestic animals has gained importance in recent years due to the recognition of the physiological, behavioral, and endocrine consequences of acute pain on animal production, welfare, and animal model validity. Current approaches to identifying acute pain mainly rely on behavioral-based scales, quantifying pain-related biomarkers, and the use of devices monitoring sympathetic activity. Infrared thermography is an alternative that could be used to correlate the changes in the superficial temperature with other tools and thus be an additional or alternate acute pain assessment marker. Moreover, its non-invasiveness and the objective nature of its readout make it potentially very valuable. However, at the current time, it is not in widespread use as an assessment strategy. The present review discusses scientific evidence for infrared thermography as a tool to evaluate pain, limiting its use to monitor acute pain in pathological processes and invasive procedures, as well as its use for perioperative monitoring in domestic animals.Alexandra L. Whittaker, Ramon Muns, Dehua Wang, Julio Martínez-Burnes, Ismael Hernández-Ávalos, Alejandro Casas-Alvarado, Adriana Domínguez-Oliva, and Daniel Mota-Roja

    Agrárpiaci Jelentések, Baromfi

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    Amerikai Egyesült Államok agrárminisztériumának (USDA) májusban megjelent jelentése szerint az USA csirkehústermelése 4,6 millió tonna körül alakult 2017 első negyedévében, ami 2 százalékkal haladta meg az előző év azonos időszakának kibocsátását. Az Európai Bizottság adatai alapján 2017 első 20 hetében 178 euró/100 kilogramm volt az egész csirke uniós átlagára, kismértékben csökkent az előző év hasonló időszakának átlagárához viszonyítva. Magyarországon a vágócsirke élősúlyos termelői ára (245,9 forint/kilogramm) 4,3 százalékkal volt alacsonyabb 2017 20. hetében az egy évvel korábbinál

    Veganism and animal welfare, scientific, ethical, and philosophical arguments

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    Published Online: May 1, 2023The justification for this review article is to understand the position of vegans and those individuals who consume food of animal origin from an unbiased perspective but with a grounding in scientific evidence. This will provide people who eat meat with scientific and ethical arguments to defend their alimentary autonomy in the context of the moral conflict that has emerged in societies regarding the consumption of meat and animal products, which is criticized –sometimes even attacked– by activists, ovolactovegetarians, or vegetarians with alimentary habits that stress ethical and moral respect for animals. These individuals refuse to eat meat and animal products but sometimes show disrespect for those who do. In recent decades, veganism and vegetarianism have reached an apogee in some western societies where they are often considered a healthy option for humans that simultaneously fosters animal and environmental welfare. While those diets may provide numerous benefits, they can also entail health risks by failing to provide balance and necessary dietary supplements. Various researchers concur that they are not appropriate for pregnant women, children, or carnivorous or omnivorous pets. Our review of scientific articles in favor and against dietary regimens that lack protein of animal origin leads to the conclusion that these dietary changes, on their own, do not reduce animal suffering or the contamination generated by the meat, dairy, and poultry industries. Finally, it is important to consider that, despite the popular opinion that vegetarianism and veganism are healthy diet alternatives, the diet must be individualized and well-balanced according to each stage of their life cycle.Daniel Mota-Rojas, Alexandra L. Whittaker, Leonardo Thielo de la Vega, Marcelo Ghezzi, Karina Lezama-García, Adriana Domínguez-Oliva, Isabel Falcón, Alejandro Casas-Alvarado, María Alonso-Spilsbur
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